Dynamic changes in murine forebrain miR - 211 expression associate with cholinergic imbalances and epileptiform activity
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Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity.
Epilepsy is a common neurological disease, manifested in unprovoked recurrent seizures. Epileptogenesis may develop due to genetic or pharmacological origins or following injury, but it remains unclear how the unaffected brain escapes this susceptibility to seizures. Here, we report that dynamic changes in forebrain microRNA (miR)-211 in the mouse brain shift the threshold for spontaneous and p...
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تاریخ انتشار 2017